The CFL2 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CFL2, and Cofilin 2. This antibody recognizes Human, Mouse, and Rat antigen. The CFL2 Rabbit pAb Antibody has been validated for the following applications: Immunofluorescence, and Western Blot.
Description
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3 (PubMed:19752190). It has the ability to bind G-and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. May play a role during the exchange of alpha-actin forms during the early postnatal remodeling of the sarcomere